drug development

A new drug reduces risk of psychosis relapse in patients with dementia

Pimavanserin has not received approval from the FDA, but study results are encouraging

Alzheimer's drugs targeting amlyoid plaque may be doomed to fail

In a study of the cause of Alzheimer's, cognitive decline tracked something other than high levels of amyloid plaques

How scientists developed the most popular anesthetic used today, without totally knowing how it works

The "milk of amnesia" is relatively new, and is predated by centuries of weak attempts at pain relief

Yeast could soon make psilocybin cheaper than their magic mushroom cousins can

New work could even lead to psychedelic intermediates not previously available in large quantities

Drug repurposing gave remdesivir its second, third, and fourth chance

The antiviral has had a charmed life, failing multiple times but coming back again and again

A failed Alzheimer's drug stops cancer cells from shedding their coats and hiding from the immune system

A chance reading and a fortuitous overlap between Alzheimer's and multiple myeloma biology gave a failed drug new life

New research shows how protein aggregates destroy muscle cells

These findings have important implications for the treatment of myofibrillar myopathies, a set of diseases that affect the muscles

Researchers optimized a reaction involving DEAD to reduce chemical waste

The Mitsunobu reaction is key to using alcohols in organic chemistry, but it also generates considerable chemical waste

New types of drugs, called PROTACs, melt cancer-causing proteins away

Researchers from Yale and Oregon Health and Science universities have now used this approach to treat chronic myeloid leukemia cells

We have many tools in the fight against antibiotic resistance, and we should consider not using them

New studies hold promise for treating tuberculosis — but also suggest that sometimes the best course of action in treating infections is no action

Is your gut microbiome stealing your drugs?

New research identifies how our gut microbiomes interfere with the medications we take, and offers the possibility of medicine personalized to our gut bacteria.

Scientists have discovered how to slow the process that creates drug-resistant cancer

Blocking the path of tumor evolution improves treatment outcomes